INDIANAPOLIS, July 23, 2018 /PRNewswire/ -- Lanthim Pharmaceuticals (Lanthiso Biopharmaceuticals) (Nasdaq: LANTI) today announced that the U. S. Food and Drug Administration (FDA) approved baclofen (Lioresal 10 mg/5 mL) and baclofen (Lioresal 5 mg/5 mL) as first-in-line treatments for severe spasticity associated with multiple sclerosis (MS). Baclofen is an FDA-approved treatment for MS, marketed as Lioresal (Baclofen Tablets) 10 mg, and Lioresal 5 mg, which are oral formulations of Lioresal 10 mg. Lioresal 5 mg, in combination with other treatments, is indicated for the short-term treatment of post-stroke symptoms, and is approved for a maximum of two months of treatment for severe spasticity associated with MS. Lanthim Pharmaceuticals also launched Lioresal 10 mg/5 mL in the United States on July 22, 2018 for the treatment of acute and chronic spasticity. Lanthim is the sole manufacturer of Lioresal 10 mg/5 mL in the United States.
Lioresal is indicated for the short-term treatment of post-stroke symptoms, and is approved for a maximum of two months of treatment for severe spasticity associated with MS. Lanthim is the sole manufacturer of Lanthim 10 mg/5 mL, the first-in-line treatment for MS, and is approved for a maximum of two months of treatment for severe spasticity associated with MS.About Lanthim Pharmaceuticals
Lanthiso Biopharmaceuticals is a privately held company based in Bothell, Washington. Lanthim is developing and commercializing treatments for MS, the most severe MS-related condition worldwide, for the treatment of chronic pain and to help patients with MS manage their pain. Lanthim is also manufacturing and developing a drug for the treatment of MS, Lioresal 10 mg/5 mL for chronic pain, and Lioresal 5 mg, Lanthim 10 mg/5 mL for chronic pain.
Baclofen Tablets are for the treatment of muscle spasms or stiffness caused due to neurological conditions. Baclofen tablets contains the active substance Baclofen, which belongs to a group of medicines called muscle relaxants. These tablets are used to treat muscle spasms caused by neurological disorders.
Baclofen Tablets are used to treat muscle spasms or stiffness caused by neurological conditions. These tablets are used to treat muscle spasms due to cerebral palsy, cerebral hemorrhage or other neurological conditions. Treatment of spasms may be stopped by the doctor at once.
Baclofen Tablets may also be used for purposes not listed in this medication guide.
Each tablet contains 3. mg (16 or 32.38 mg) of Baclofen.
Active ingredient: Baclofen sodium
Dosage:
For adults: 10 to 60 mg/day (base of the dosage) by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused due to cerebral palsy, cerebral hemorrhage or other neurological conditions. For children: 10 to 12 mg/kg/day (base of the dosage) by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused due to juvenile skeletal muscle disorders. For adolescents: 10 to 20 mg/kg/day (base of the dosage) by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused by cerebral hemorrhage or other neurological disorders. For the treatment of spasms in adults: 10 to 60 mg/day (base of the dosage) by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused by cerebral hemorrhage or other neurological disorders. (1,2)
Directions for Use:
The usual dosage is 10 to 20 mg/day by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused due to cerebral palsy, cerebral hemorrhage or other neurological disorders. The usual daily dosage for spasms in adults is 10 to 20 mg/day by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused due to cerebral hemorrhage or other neurological disorders. (1)
The dosage for children is adult: 10 to 40 mg/kg/day (base of the dosage) by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused by cerebral hemorrhage or other neurological disorders.
The dosage for adults is adult: 10 to 40 mg/kg/day (base of the dosage) by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused due to juvenile skeletal muscle disorders. The usual daily dosage for spasms in adults is 10 to 20 mg/day by mouth (every 3-4 hours) with or without food for muscle spasms or stiffness caused by cerebral hemorrhage or other neurological disorders.
The use of Baclofen Tablets for the treatment of spasms or stiffness due to cerebral palsy or cerebral hemorrhage in children and adolescents is not recommended.
Contraindications:
Baclofen Tablets are contraindicated in patients who have had hypersensitivity to Baclofen or to any of the excipients. When these conditions are present, treatment with Baclofen Tablets is considered to be contraindicated. Also, treatment with Baclofen Tablets may be necessary in patients who are receiving intrathecal baclofen therapy. In some countries, such as the UK, where Baclofen Tablets are not available, intrathecal baclofen therapy may be used.
Adverse Reactions:
The most common adverse reactions reported during the first week of treatment with Baclofen Tablets were muscle spasms and rigidity.
More serious reactions were reported in the 10- to 15-week treatment period, in which signs were reported that included seizures (epilepsy); hallucinations (hypothermia); seizures and convulsions (convulsion); convulsions with severe drowsiness and coma.
The most common adverse reactions were dizziness, dry mouth, constipation, insomnia and dizziness due to Baclofen Tablets.
There were no differences in the clinical and electrocardiographic findings between the treatment arms.
Baclofen is a non-selective GABAB receptor agonist and is not effective against the GABAB agonist []. The mechanism of action of baclofen is unclear, but some evidence suggests that this drug may increase the amount of cGMP in the spinal cord [, ]. In the present study, the effect of baclofen on the spinal cord was studied using rats. The effects of baclofen on the rat spinal cord were measured using microdialysis. The results showed that the baclofen dose in this study was not different from the control group, but baclofen dose was more than the control group, and baclofen dose induced the most effects at 5- to 7-fold increase in the spinal cord area. In addition, there was a significant difference between the two groups in the level of cGMP (P<0.05) and the level of the baclofen (P<0.05) in the spinal cord area. At the end of the study, the doses of baclofen were kept below the maximum recommended dose of baclofen (10 mg/kg, i.m.). The results of the study confirmed that the baclofen dose was the least affected by the effect of baclofen on the spinal cord area. The results of this study showed that the baclofen dose was the least affected by the effect of baclofen on the spinal cord area. Therefore, baclofen is an effective drug that has a significant effect on the spinal cord in the rat.
VIDEOThe effects of baclofen on the spinal cord were measured using microdialysis.
The effect of baclofen on the spinal cord was studied using rats. The results of this study showed that the baclofen dose in this study was not different from the control group, but baclofen dose was more than the control group, and baclofen dose induced the most effects at 5- to 7-fold increase in the spinal cord area.
The effects of baclofen on the spinal cord were studied using rats.
Baclofen is a prescription muscle relaxant. It is used to treat muscle and joint pain, spasms or stiffness in the brain, back, or pelvic area.
Baclofen is used to treat muscle pain or painful and otherwise related conditions as it helps the body get rid of muscle spasms, stiffness, and/or discomfort. The medicine is also used to treat pain in muscles.
Side Effects:Mood changes, such as anxiety, irritability, agitation, trouble sleeping, or hallucinations, have been reported in some patients taking baclofen. If you experience any of these symptoms, stop using the medicine and contact your doctor immediately.
Possible side effects:In the last two weeks, I’ve been having trouble finding a source of medication to help. I found a website that sells a muscle relaxant calledBaclofen(generic of the drug, which is also known by the brand name Lyrica). I found it online and was able to find it in the pharmacy section of my home town. I’ve tried other muscle relaxants but have found nothing that worked for me.
I was able to get a brand-name Lyrica for about $15.00 but that’s not the price of the brand name and is it worth the hassle of a visit?
I would like to find a website that would allow people to order Baclofen online from Canada instead of seeing me in person? I’ve tried the website and they haven’t found anything to say for me. I don’t have the time or desire to get to the bottom of the problem.
I’ve been looking for a website to take a look at Baclofen for the past year and a half, and I’ve been trying to find it online for the past week or so. It seems that the website is only interested in pharmacies. It would be great if they could help me find the best pharmacy to fill my needs.
I have a website that is currently in the process of being set up, and I’ll add to my search results next week. My initial search for it did not work either, though the website has been shut down for a couple of weeks because of the lack of traffic to the website. My website is located in Canada, so I’m not sure what they are offering to help me with the cost of shipping to my home town.
I’ll try to get this going in a bit more detail when I get back to the site. Any help is appreciated!
I was just wondering if anyone else has had this experience and if it’s possible to use it to buy Baclofen? I am on a 12 week cycle of this drug.
This is the most common issue with prescription drugs.
Related:
I’m interested in trying out the website. I’m considering a website that will allow me to purchase it from Canada and allow me to place orders in person. If this seems too good to be true, I’d like to see a website that will allow me to get the product to my home town and deliver it in a timely manner.
I’m not sure if this will be the best idea, or if anyone else has had this issue with the website? I’m trying to find a website to take a look at to help others with the cost of medications. If anyone else has experience with this problem and would like to contribute to further this effort, I would be much appreciate it.
Thanks again for all your help!
This is what I’m looking for:The website is available in Canada and the website is available in the United States. We are unable to contact any of the Canadian online pharmacies that we have been able to find, although our pharmacists have been able to fill the order on the website. It is difficult to get a pharmacy to deliver a product to your home town in Canada, but that is what we do. We would be more than happy to help.
The website has been out of date for several months and we’re trying to get it back in order. I’m hoping the website will be able to answer any questions about the cost and availability of the drug. I’ll probably have to try to get back to my pharmacy for more information.
Thanks again for all this help!
Here are the links to the sites:I was just thinking of trying to find a website that would be able to do all this for me. It’s a little hard to find online, but it seems to be a reasonable option for me to try. I’ve tried several different website options, including the website of the Canadian site and they seem to be looking for it as well. I’d appreciate any help you can provide.
Stade de France Pharmacy